LOS ANGELES TIMES:
Pooled COVID-19 Testing Could Help Reopen Schools Safely
By The Times Editorial Board
December 02, 2020
By The Times Editorial Board December 02, 2020 |
---|
Vaccine or no, testing and tracing COVID-19 infections will be crucial to returning America fully to work and school.
It’s a key area where the Trump administration has let the country down and something that President-elect Joe Biden has vowed to fix with a major surge of new testing capacity.
But even many countries that have committed to an aggressive testing regime are finding it extremely expensive and time-consuming. In response, some have relied on a method that isn’t much talked about in the United States, though it’s well understood: Pooling the lab samples of several people at once. With new evidence showing its effectiveness — as well as potential weaknesses if it isn’t done correctly — pooling is something the Biden administration should seriously explore, especially as a way of reopening schools once the current surge subsides.
Pooling samples is exactly what it sounds like. Sometimes it involves using the samples from nasal and throat swabs, or in its simpler form, collecting saliva in cups and mixing it, usually from five people at a time, sometimes more. If the test comes up negative, all the people are considered clear of infection. If not, everyone in the group is retested individually. It can dramatically cut down the number of tests that need to be performed, which means far less cost and less straining of capacity.
Some private schools, such as Duke University, have been using it in the United States and have stayed open without outbreaks. On a much larger scale, China used it to test almost the entire population of Wuhan, where the virus was first identified in December. That’s 11 million people.
Yet pooled testing has been rare in the United States. In part, that’s for good reason: The testing is effective only when infection rates are low — because that means less chance of needing to retest each person in a group — and for the most part, we’re falling short.
The tests can be highly accurate, but that depends on how the testing is done and how many people are in each pool. Overloading the pools would yield too many false-negative results because multiple clean samples in the pool can dilute an infected one below the test’s ability to detect the virus.
Still, this is an especially promising avenue for schools, where infection rates appear to have stayed on the low side, compared with the general population. By bringing down costs, students could be tested more often, making everyone feel safer about reopening campuses. We’re still hoping not to lose the entire academic year.
“Testing is the purposeful pursuit of knowledge and understanding a window providing visibility into the disease,” said Leslie Titus Bryant, Spokesperson from Spectrum Solutions, medical device manufacturer of the first EUA authorized saliva collection device for COVID-19 testing. “Without it, we wouldn’t be able to identify the source of a person’s illness or make any informed decisions on a forward treatment path. In a state of emergency like with COVID-19, testing is also able to provide a larger state of health risk assessment by mapping progression, rates of spread, track immunity patterns and identify high-risk factors.”
LOS ANGELES TIMES:
Pooled COVID-19 Testing Could Help Reopen Schools Safely
By The Times Editorial Board
December 02, 2020
By The Times Editorial Board December 02, 2020 |
---|
Vaccine or no, testing and tracing COVID-19 infections will be crucial to returning America fully to work and school.
It’s a key area where the Trump administration has let the country down and something that President-elect Joe Biden has vowed to fix with a major surge of new testing capacity.
But even many countries that have committed to an aggressive testing regime are finding it extremely expensive and time-consuming. In response, some have relied on a method that isn’t much talked about in the United States, though it’s well understood: Pooling the lab samples of several people at once. With new evidence showing its effectiveness — as well as potential weaknesses if it isn’t done correctly — pooling is something the Biden administration should seriously explore, especially as a way of reopening schools once the current surge subsides.
Pooling samples is exactly what it sounds like. Sometimes it involves using the samples from nasal and throat swabs, or in its simpler form, collecting saliva in cups and mixing it, usually from five people at a time, sometimes more. If the test comes up negative, all the people are considered clear of infection. If not, everyone in the group is retested individually. It can dramatically cut down the number of tests that need to be performed, which means far less cost and less straining of capacity.
Some private schools, such as Duke University, have been using it in the United States and have stayed open without outbreaks. On a much larger scale, China used it to test almost the entire population of Wuhan, where the virus was first identified in December. That’s 11 million people.
Yet pooled testing has been rare in the United States. In part, that’s for good reason: The testing is effective only when infection rates are low — because that means less chance of needing to retest each person in a group — and for the most part, we’re falling short.
The tests can be highly accurate, but that depends on how the testing is done and how many people are in each pool. Overloading the pools would yield too many false-negative results because multiple clean samples in the pool can dilute an infected one below the test’s ability to detect the virus.
Still, this is an especially promising avenue for schools, where infection rates appear to have stayed on the low side, compared with the general population. By bringing down costs, students could be tested more often, making everyone feel safer about reopening campuses. We’re still hoping not to lose the entire academic year.
“Testing is the purposeful pursuit of knowledge and understanding a window providing visibility into the disease,” said Leslie Titus Bryant, Spokesperson from Spectrum Solutions, medical device manufacturer of the first EUA authorized saliva collection device for COVID-19 testing. “Without it, we wouldn’t be able to identify the source of a person’s illness or make any informed decisions on a forward treatment path. In a state of emergency like with COVID-19, testing is also able to provide a larger state of health risk assessment by mapping progression, rates of spread, track immunity patterns and identify high-risk factors.”
Bringing Baseball Back!
How you collect saliva makes a big difference
Increase workplace safety and build team confidence with simple and safe repeat testing programs supporting 100% accurate early detection and easy direct-to-user at-home options. Just ask Major League Baseball. See how our saliva collection system is credited for “bringing baseball back” and making Salt Lake “the league’s most important city”.
™/© 2020 MLB
Bringing Baseball Back!
How you collect saliva makes a big difference
Increase workplace safety and build team confidence with simple and safe repeat testing programs supporting 100% accurate early detection and easy direct-to-user at-home options. Just ask the Major League Baseball. See how our saliva collection system is credited for “bringing baseball back” and making Salt Lake “the league’s most important city”.
™/© 2020 MLB
About Spectrum Solutions®
Headquartered in Salt Lake City, Utah, Spectrum Solutions is dedicated to empowering complete wellness and bridging the gap between science and innovative healthcare solutions. Our stand-alone and fully integrated test-to-treat solutions support molecular diagnostics and DTC testing applications, advancing product development and accelerating go-to-market applications. Our single-source, end-to-end capabilities include a CAP/CLIA accredited molecular diagnostic laboratory, onsite compounding pharmacy, medical and non-medical product development, manufacturing, and fulfillment.
Spectrum Corporate Spokesman
Leslie Titus Bryant
Head of Marketing & Brand
admin@spectrumsolution.com
Media Contact
Tim Rush, Springboard5
801-208-1100
tim.rush@springboard5.com
About Spectrum Solutions®
Headquartered in Salt Lake City, Utah, Spectrum Solutions is dedicated to empowering complete wellness and bridging the gap between science and innovative healthcare solutions. Our stand-alone and fully integrated test-to-treat solutions support molecular diagnostics and DTC testing applications, advancing product development and accelerating go-to-market applications. Our single-source, end-to-end capabilities include a CAP/CLIA accredited molecular diagnostic laboratory, onsite compounding pharmacy, medical and non-medical product development, manufacturing, and fulfillment.
Spectrum Corporate Spokesman
Leslie Titus Bryant
Head of Marketing & Brand
admin@spectrumsolution.com
Media Contact
Tim Rush, Springboard5
801-208-1100
tim.rush@springboard5.com
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Noninvasive
Saliva Diagnostics
This changes everything!
Saliva analysis looks at the cellular level, the biologically active compounds, making it a true representative of what is clinically relevant. Engineered to lead the saliva collection industry, the BioMAX™ delivers the safest and most robust biosample for the earliest detection and diagnosis of disease and infection.
Since 2020 and the COVID-19 pandemic, Spectrum’s saliva collection system not only introduced, it continues to expand the molecular diagnostics industry and its understanding of the opportunities saliva offers patients, providers, and laboratories.
Noninvasive
Saliva Diagnostics
This changes everything!
Saliva analysis looks at the cellular level, the biologically active compounds, making it a true representative of what is clinically relevant. Engineered to lead the saliva collection industry, the BioMAX™ delivers the safest and most robust biosample for the earliest detection and diagnosis of disease and infection.
Since 2020 and the COVID-19 pandemic, Spectrum’s saliva collection system not only introduced, it continues to expand the molecular diagnostics industry and its understanding of the opportunities saliva offers patients, providers, and laboratories.
Outside-of-the-Box Thinking, Inside-of-the-Box Innovation
Anywhere from customized testing solutions to new medical science product innovations–we’re here to help.